Jianghong Rao Lab In the Departments of Radiology and Chemistry


2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 |

Prof. Rao's Publications from his graduate years


102. Suchismita Mohanty, Zixin Chen, Kai Li, Goreti Ribeiro Morais, Jessica Klockow, Ketan Yerneni, Laura Pisani, Frederick T. Chin, Siddhartha Mitra, Samuel Cheshier, Edwin Chang, Sanjiv Sam Gambhir, Jianghong Rao, Paul M. Loadman, Robert A Falconer and Heike E Daldrup-Link. A novel theranostic strategy for MMP-14 expressing glioblastomas impacts survival. Molecular Cancer Therapeutics. 2017. DOI:10.1158/1535-7163.MCT-17-0022

101. Michelle L. James, Nadia P. Belichenko, Adam J. Shuhendler, Aileen Hoehne, Lauren E. Andrews, Christina Condon, Thuy-Vi V. Nguyen, Vladimer Reiser, Paul Jones, William Trigg, Jianghong Rao, Sanjiv S. Gambhir and Frank M. Longo. [18F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease. Theranostics. 2017. DOI:10.7150/thno.17666

100. Hee-Jeong Yang, Ying Kong, Yunfeng Cheng, Harish Janagama, Hany Hassounah, Hexin Xie, Jianghong Rao and Heffrey D. Cirillo. Real-time Imaging of Mycobacterium tuberculosis, Using a Novel Near-Infrared Fluorescent Substrate. Journal of Infectious Disease. 2017. DOI: 10.1093/infdis/jiw298

99. Liyang Cui and Jianghong Rao. Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes. Nanomedicine and Nanobiotechnology. 2017. DOI:10.1002/wnan.1418

| Back to top |


98. Fatemeh Nooshabadi, Hee-Jeong Yang, Yunfeng Cheng, Madeleine S. Durkee, Hexin Xie, Jianghong Rao, Jeffrey D. Cirillo and Kristen C. Maitland. Intravital excitation increases detection sensitivity for pulmonary tuberculosis by whole-body imaging with β-lactamase reporter enzyme fluorescence. Journal of Biophotonics. 2016. DOI:10.1002/jbio.201600132

97. Yiping Chen, Yunlei Xianyu, Jing Wu, Wenfu Zheng, Jianghong Rao and Xingyu Jiang. Point-of-care detection of β-Lactamase in milk with a universal fluorogenic probe. Analytical Chemistry. 2016. DOI:10.1021/acs.analchem.6b01122

96. Jianghong Rao and Christopher H. Contag. More chemistry is needed for molecular imaging. Journal of Controlled Release. 2016.DOI:10.1021/acs.bioconjchem.6b00056

95. Kanyi Pu, Niladri Chattopadhyay and Jianghong Rao. Recent advances of semiconducting polymer nanoparticles inin vivo molecular imaging. Journal of Controlled Release. 2016. DOI:10.1016/j.jconrel.2016.01.004

| Back to top |


94. Adam J. Shuhendler*, Deju Ye*, Kimberly D*. Brewer, Magdalena Bazalova-Carter, Kyung-hyun Lee, Paul Kempen, Dane K. Wittrup Edward E. Graves, Brian Rut and Jianghong Rao. Molecular magnetic resonance imaging of tumor response to therapy. scientific reports. 2015.   doi:10.1038/srep14759( *Co-first author)

93. Fengjiao Lyu, Manqi Xu, Yunfeng Cheng, Jinghang Xie, Jianghong Rao and Sindy K. Y. Tang. Quantitative detection of cells expressing BlaC using droplet-based microfluidics for use in the diagnosis of tuberculosis. Biomicrofluidics. 2015. doi: 10.1063/1.4928879

92. Kanyi Pu, Jianguo Mei, Jesse V. Jokerst, Guosong Hong, Alexander L. Antaris, Niladri Chattopadhyay, Adam J. Shuhendler, Tadanori Kurosawa, Yan Zhou, Sanjiv S. Gambhir, Zhenan Bao, Jianghong Rao. Diketopyrrolopyrrole-Based semiconducting polymer nanoparticles for in vivo photoacoustic imaging. Advanced Materials. 2015. DOI: 10.1002/adma.201502285

91. Mikael Palner, Kanyi Pu, Shirley Shao, Jianghong Rao. Semiconducting polymer nanoparticles with persistent near-infrared luminescence for in vivo optical imaging. Angewandte Chemie. 2015. DOI: 10.1002/anie.201502736

90. Mikael Palner, Bin Shen, Jongho Jeon, Jianguo Lin, Frederick T. Chin, Jianghong Rao. Preclinical Kinetic Analysis of the Caspase-3/7 PET Tracer 18F-C-SNAT: Quantifying the changes in blood flow and tumor retention after chemotherapy. Journal of Nuclear Medicine. 2015. doi: 10.2967/jnumed.115.155259

80. Timothy H Witney*, Aileen Hoehne*, Robert E Reeves, Ohad Ilovich, Mohammad Namavari, Bin Shen, Frederick T Chin, Jianghong Rao, Sanjiv S Gambhir. A systematic comparison of 18F-C-SNAT to established radiotracer imaging agents for the detection of tumor response to treatment. Clinical Cancer Research. 2015. doi:10.1158/1078-0432.CCR-14-3176 ( *Co-first author)

79. Lina Cui, Jianghong Rao. 2-Cyanobenzothiazole (CBT) condensation for site-specific labeling of proteins at the terminal cysteine residues. Methods Mol Biol. 2015. doi: 10.1007/978-1-4939-2272-7_5

78. Hossein Nejadnik*, Deju Ye*, Olga D. Lenkov, Jessica Donig, John E. Martin, Rostislav Castillo, Nikita Derugin, Barbara Sennino, Jianghong Rao, and Heike E. Daldrup-Link. Magnetic resonance imaging of stem cell apoptosis in arthritic joints with a caspase activatable contrast agent. ACS Nano 2015. doi: 10.1021/nn504494c ( *Co-first author)

77. Tzu-Yin Wang, Jung Woo Choe, Kanyi Pu, Rammohan Devulapally, Sunitha Bachawal, Steven Machtaler, Sayan Mullick Chowdhury, Richard Luong, Lu Tian, Butrus Khuri-Yakub, Jianghong Rao, Ramasamy Paulmurugan, Jürgen K. Willmann. Ultrasound-guided delivery of microRNA loaded nanoparticles into cancer. Journal of Control Release 2015. doi:10.1016/j.jconrel.2015.02.018

| Back to top |


76. Deju Ye, Adam J. Shuhendler, Prachi Pandit, Kimberly D. Brewer, Sui Seng Tee, Lina Cui, Grigory Tikhomirov, Brian Rut, Jianghong Rao. Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis. Chemical Science 2014. doi10.1039/C4SC01392A.

75. Deju Ye, Prachi Pandit, Paul Kempen, Jianguo Lin, Liqin Xiong, Robert Sinclair, Brian K Rutt, Jianghong Rao. Fluorogenic Redox-triggered Self-Assembly of Gadolinium-based MRI Probes for Sensing Reducing Environment. Bioconjugate chemistry 2014. doi: 10.1021/bc500254g.

74. Yunfeng Cheng, Hexin Xie, Preeti Sule, Hany Hassounah, Edward A Graviss, Ying Kong, Jeffrey D Cirillo, Jianghong Rao. Fluorogenic Probes with Substitutions at the 2 and 7 Positions of Cephalosporin are Highly BlaC‐Specific for Rapid Mycobacterium Tuberculosis Detection. Angewandte Chemie 2014. doi: 10.1002/ange.201405243.

73. Xinhui Su, Kai Cheng, Jongho Jeon, Bin Shen, Gianina Teribele Venturin, Xiang Hu, Jianghong Rao, Frederick T Chin, Hua Wu, Zhen Cheng. Comparison of Two Site-Specifically 18F-Labeled Affibodies for PET Imaging of EGFR Positive Tumors. Mol. Pharmaceutics 2014. doi10.1021/mp5003043.

72. Deju Ye*, Adam J Shuhendler*, Lina Cui, Ling Tong, Sui Seng Tee, Grigory Tikhomirov, Dean W Felsher, Jianghong Rao. Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo. Nature Chem 2014. doi:10.1038/nchem.1920. ( *Co-first author)

71. Haibin Shi*, Yunfeng Cheng*, Kyung Hyun Lee, Robert F Luo, Niaz Banaei, and Jianghong, Rao. Engineering Stereochemistry of Cephalosporin for Specific Detection of Carbapenemase-Expressing Pathogenic Bacteria. Angew. Chem. Int. Ed. In press. DOI: 10.1002/anie.201402012R1. ( *Co-first author)

70. Pu K,* Shuhendler AJ,* Valta MP,*, Cui L, Saar M, Peehl DM, Rao J. Phosphorylcholine-Coated Semiconducting Polymer Nanoparticles as Rapid and Efficient Labeling Agents for In Vivo Cell Tracking. Adv Healthc Mater. 2014 Mar 25. doi: 10.1002/adhm.201300534. *Co-first author.

69. Shuhendler AJ,* Pu K,*, Cui L, Uetrecht JP, Rao J. Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing. Nat Biotechnol. 2014 Mar 23. doi: 10.1038/nbt.2838. *Co-first author.

68. Pu K,* Shuhendler AJ,*, Jokerst JV, Mei J, Gambhir SS, Bao Z, Rao J. Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice. Nat Nanotechnol. 2014,9, 233-239 .doi: 10.1038/nnano.2013.302. *Co-first author.

| Back to top |


67. Ansari, C., Tikhomirov, G. A., Hong, S. H., Falconer, R. A., Loadman, P. M., Gill, J. H., Castaneda, R., Hazard, F. K., Tong, L., Lenkov, O. D., Felsher, D. W., Rao, J. and Daldrup-Link, H. E, Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy. Small (DOI: 10.1002/smll.201301456)

66. Chapman S, Dobrovolskaia M, Farahani K, Goodwin A, Joshi A, Lee H, Meade T, Pomper M, Ptak K, Rao J, Singh R, Sridhar S, Stern S, Wang A, Weaver JB, Woloschak G, YangL. Nanoparticles for cancer imaging: The good, the bad, and the promise. Nano Today, 2013 (DOI: 10.1016/j.nantod.2013.06.001)

65. Dragulescu-Andrasi A, Kothapalli S, Tikhomirov GA, Rao J and Gambhir SS. Activatable Oligomerizable Imaging Agents for Photoacoustic Imaging of Furin-Like Activity in Living Subjects, Journal of the American Chemical Society 2013 135 (30), 11015-11022 (DOI: 10.1021/ja4010078)

64. Pu K, Shuhendler AJ, and Rao J. Semiconducting Polymer Nanoprobe for In Vivo Imaging of Reactive Oxygen and Nitrogen Species . Angew. Chem. Int. Ed. 2013. (DOI: 10.1002/anie.201303420)

63. Shen B, Jeon J, Palner M, Ye D, Shuhendler A, Chin FT, Rao J. Positron Emission Tomography Imaging of Drug-Induced Tumor Apoptosis with a Caspase-Triggered Nanoaggregation Probe. Angew. Chem. Int. Ed. 2013. (DOI: 10.1002/anie.201303422)

62. Xiong LQ, Shen B, Behera D, Gambhir SS, Chin FT, Rao J. Synthesis of ligand-functionalized water-soluble [F-18]YF3 nanoparticles for PET imaging. Nanoscale . 2013, 5, 8, 3253-3256. (DOI: 10.1039/c3nr00335c)

| Back to top |


61. Lee MK, Williams J, Twieg RJ, Rao J, Moerner WE. Enzymatic activation of nitro-aryl fluorogens in live bacterial cells for enzymatic turnover-activated localization microscopy. Chemical Science . 2012, 4, 1, 220-225. (DOI: 10.1039/c2sc21074f)

60. Xiong LQ, Shuhendler AJ, Rao J..Self-luminescing BRET-FRET near-infrared dots for in vivo lymph-node mapping and tumour imaging. Nature Communications . 2012, 3, 1193. (DOI: 10.1038/ncomms2197)

59. Jeon J*, Lee KH*, Rao J. A Strategy to Enhance the Binding Affinity of Fluorophore-Aptamer Pairs for RNA Tagging with Neomycin Conjugation, Chem Commun. 2012, 48, 10034-10036 (*; Equal contribution) (DOI: 10.1039/c2cc34498j)

58. Xie HX, Mire J, Kong Y, Chang MH, Hassaounah HA, Thornton CN, Sacchettini JC, Cirillo JD, Rao J.. Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probe. Nature Chemistry . 2012, 4, 10, 802-809. (DOI: 10.1038/NCHEM.1435)

57. Jeon J, Shen B, Xiong LQ, Miao Z, Lee KH, Rao J, Chin FT. Efficient Method for Site-Specific F-18-Labeling of Biomolecules Using the Rapid Condensation Reaction between 2-Cyanobenzothiazole and Cysteine. Bioconjugate Chemistry . 2012, 23, 9, 1902-1908. (DOI: 10.1021/bc300273m)

56. Conley NR, Dragulescu-Andrasi A, Rao J, Moerner WE. A Selenium Analogue of Firefly D-Luciferin with Red-Shifted Bioluminescence Emission. Angew Chem Int Ed Engl. 2012 Feb 17 . PMID: 22344705

| Back to top |


55. Xia Z, Xing Y, Jeon J, Kim YP, Gall J, Dragulescu-Andrasi A, Gambhir SS, Rao J. Immobilizing reporters for molecular imaging of the extracellular microenvironment in living animals. ACS Chem Biol. 2011 Oct 21;6(10):1117-26 . PMID: 21830814

54. Daldrup-Link HE, Golovko D, Ruffell B, Denardo DG, Castaneda R, Ansari C, Rao J, Tikhomirov GA, Wendland MF, Corot C, Coussens LM. MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles. Clin Cancer Res. 2011 Sep 1;17(17):5695-704 . PMID: 21791632

53. Liang G, Ronald J, Chen Y, Ye D, Pandit P, Ma ML, Rutt B, Rao J. Controlled self-assembling of gadolinium nanoparticles as smart molecular magnetic resonance imaging contrast agents. Angew Chem Int Ed Engl. 2011 Jul 4;50(28):6283-6 . PMID: 21618367

52. Razgulin A, Ma N, Rao J. Strategies for in vivo imaging of enzyme activity: an overview and recent advances. Chem Soc Rev. 2011 Jul;40(7):4186-216 . PMID: 21552609

51. Kong Y, Shi Y, Chang M, Akin AR, Francis KP, Zhang N, Troy TL, Yao H, Rao J, Cirillo SLG, Cirillo JD. Whole-body imaging of infection using bioluminescence. Current Protocols in Microbiology 2011, 21, 2C.4.1-2C.4.17. PMID: 21538305

50. Kong Y, Akin AR, Francis KP, Zhang N, Troy TL, Xie H, Rao J, Cirillo SLG, Cirillo JD. Whole-body imaging of infection using fluorescence. Current Protocols in Microbiology 2011, 21, 2C.3.1-2C.3.21. PMID: 21538304

49. Zhan K, Xie H, Gall J, Ma M, Griesbeck O, Salehi A, Rao J. Real-time imaging of Rab5 activity using a prequenched biosensor. ACS Chem Biol. 2011 Jul 15;6(7):692-9 . PMID: 21506516

48. Ye D, Liang G, Ma ML, Rao J. Controlling intracellular macrocyclization for the imaging of protease activity. Angew Chem Int Ed Engl. 2011 Mar 1;50(10):2275-9. . PMID: 21351335

| Back to top |


47. Lee HD, Lord SJ, Iwanaga S, Zhan K, Xie H, Williams JC, Wang H, Bowman GR, Goley ED, Shapiro L, Twieg RJ, Rao J, Moerner WE. Superresolution imaging of targeted proteins in fixed and living cells using photoactivatable organic fluorophores. Journal of the American Chemical Society 2010, 132, 15099-15101. (Highlighted by Nature) PMID: 20936809

46. Lee J, Lee KH, Jeon J, Dragulescu-Andrasi A, Xiao F, Rao J. Combining SELEX screening and rational design to develop light-up fluorophore-RNA aptamer pairs for RNA tagging. ACS Chemical Biology 2010, 5, 1065-1074. PMID: 20809562

45. Liang G, Ren H, Rao J. A biocompatible condensation reaction for controlled assembly of nanoparticles in cells. Nature Chemistry 2010; 2: 54-60. PMID: 21124381

44. Kong Y, Yao H, Ren H, Subbian S, Cirillo SL, Sacchettini JC, Rao J, Cirillo JD. Imaging tuberculosis with endogenous beta-lactamase reporter enzyme fluorescence in live mice. Proc Natl Acad Sci U S A. 2010, 107(27), 12239-44. PMID: 20566877

43. Ma N, Marshall AF, Gambhir SS, Rao J. Facile synthesis, silanization, and biodistribution of biocompatible quantum dots. Small. 2010, 6(14), 1520-8. PMID: 20564726

42. Ma N, Marshall AF, Rao J. Near-infrared light emitting luciferase via biomineralization. J Am Chem Soc. 2010, 132(20), 6884-5. PMID: 20441172

41. Kim YP, Daniel WL, Xia Z, Xie H, Mirkin CA, Rao J. Bioluminescent nanosensors for protease detection based upon gold nanoparticle-luciferase conjugates. Chem Commun (Camb). 2010, 46(1), 76-8. PMID: 20024298

| Back to top |


40. Ren H, Xiao F, Zhan K, Kim YP, Xie H, Xia Z, Rao J. A biocompatible condensation reaction for the labeling of terminal cysteine residues on proteins. Angew Chem Int Ed Engl. 2009, 48(51), 9658-62. PMID: 19924746

39. Dragulescu-Andrasi A, Liang G, Rao J. In Vivo Bioluminescence Imaging of Furin Activity in Breast Cancer Cells Using Bioluminogenic Substrates. Bioconjug Chem. 2009, 20 (8), 1660–1666. PMID: 19642690

38. Xing Y, Xia Z, Rao J. Semiconductor quantum dots for biosensing and in vivo imaging. IEEE Trans Nanobioscience 2009 Mar;8(1):4-12. PMID: 19304495

37. Xia Z, Rao J. Biosensing and imaging based on bioluminescence resonance energy transfer. Current Opinion in Biotechnology 2009; 20:1-8. PMID: 19216068 PDF

36. Thorne SH, Barak Y, Liang W, Bachman M, Rao J, Contag CH, Matin AC. CNOB/ChrR6, a new prodrug enzyme cancer chemotherapy. Molecular Cancer Therapeutics 2009; 8: 333-341. PMID: 19190118 PDF

35. Schipper ML, Iyer G, Koh AL, Cheng Z, Ebenstein Y, Aharoni A, Keren S, Bentolila LA, Li J, Rao J, Chen X, Banin U, Wu AM, Sinclair R, Weiss SS, Gambhir SS. Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice. Small 2009; 5: 126-134. PMID: 19051182 PDF

| Back to top |


34. Xing B, Rao J, Liu R. Novel beta-lactam antibiotic derivatives: their new applications as gene reporters, antitumor prodrugs, and enzyme inhibitors. Mini-Reviews in Medicinal Chemistry 2008; 8: 455-471. PMID: 18473935

33. Xing Y, Rao J. Quantum dot bioconjugates for in vitro diagnostics and in vivo imaging. Cancer Biomarkers 2008; 4:307-319. PMID: 19126959 PDF

32. Jiang T, Xing B, Rao J. Recent developments of biological reporter technology for detecting gene expression. Biotechnology and Genetic Engineering Reviews 2008, 25: 41-76. PMID: 21412349

31. Rao J. Shedding light on tumors using nanoparticles. ACS Nano 2008; 2: 1984-1986. PMID: 19206441 PDF

30. Xing Y, So M-K, Koh AL, Sinclair R, Rao J. Improved QD-BRET conjugates for detection and imaging. Biochemical & Biophysical Research Communications 2008; 372: 388-394. PMID: 18468518 PDF

29. So M-K, Gowrishankar G, Hasegawa S, Chung J-K, Rao J. Imaging target mRNA and siRNA-mediated gene silencing in vivo with ribozyme-based reporters. ChemBioChem 2008; 9: 2682-2691. PMID: 18972511 PDF

28. So M-K, Yao H, Rao J. HaloTag protein-mediated specific labeling of living cells with quantum dots. Biochemical & Biophysical Research Communications 2008; 374: 419-423. PMID: 18621022 PDF

27. Xia Z, Xing Y, So M-K, Koh AL, Sinclair R, Rao J. Multiplex detection of protease activity with nanosensors prepared by intein-mediated specific bioconjugation. Analytical Chemistry 2008; 80: 8649-8655. PMID: 18922019 PDF

| Back to top |


26. Gowrishankar G, Rao J. Visualizing RNA splicing in vivo. Molecular Biosystems 2007; 3: 301-307. PMID: 17460789 PDF

25. Rao J, Dragulescu-Andrasi A, Yao H. Fluorescence imaging in vivo: recent advances. Current Opinion in Biotechnology 2007; 18: 17-25. PMID: 17234399 PDF

24. Dragulescu-Andrasi A, Rao J. Chemical labeling of proteins in living cells. ChemBioChem 2007; 8: 1099-1101. PMID: 17492742 PDF

23. Yao H, Zhang Y, Xiao F, Xia Z, Rao J. QD-BRET based highly sensitive detection of proteases. Angewandte Chemie International Edition 2007; 46: 4346-4349. PMID: 17465433 PDF

22. Schipper ML, Cheng Z, Lee S-W, Keren S, Bentolila LA, Sundaresan G, Iyer G, Gheysens O, Ebenstein Y, Li J, Rao J, Chen X, Wu AM, Weiss SS, Gambhir SS. MicroPET-based biodistribution of quantum dots in living mice. Journal of Nuclear Medicine 2007; 48: 1511-1518. PMID: 17704240 PDF

21. Yao H, So M-K, Rao J. A bioluminogenic substrate for in vivo imaging of ▀-lactamase activity. Angewandte Chemie International Edition 2007; 46: 7031-7034. PMID: 17676567 PDF

20. Lin S, Xie X, Yang Y, Li Z, Cao F, Patel MR, Gheysens O, Zhang Y, Gambhir SS, Rao J, Wu J. Quantum dots imaging for embryonic stem cells. BMC Biotechnology 2007; 7: 67. PMID: 17925032 PDF

| Back to top |


19. Hasegawa S, Rao J. Modulating the splicing activity of Tetrahymena ribozyme via RNA self-assembly. FEBS Letters 2006; 580: 1592-1596. PMID: 16472807 PDF

18. So M-K, Xu C, Loening AM, Gambhir SS, Rao J. Self-illuminating quantum dot conjugates for in vivo imaging. Nature Biotechnology 2006; 24: 339-343. PMID: 16501578 PDF

17. Xu C, Xing B, Rao J. A self-assembled quantum dot probe for detecting ▀-lactamase activity. Biochemical & Biophysical Research Communications 2006; 344: 931-935. PMID: 16631595 PDF

16. Hasegawa S, Gowrishankar G, Rao J. Detection of mRNA in mammalian cells with a split ribozyme reporter. ChemBioChem 2006; 7: 925-928. PMID: 16671127 PDF Journal Cover

15. Zhang Y, So M-K, Loening AM, Yao H, Gambhir SS, Rao J. HaloTag protein-mediated site-specific conjugation of bioluminescent proteins to quantum dots. Angewandte Chemie International Edition 2006; 45: 4936-4940.PMID: 16807952 PDF

14. So M-K, Loening AM, Gambhir SS, Rao J. Creating self-illuminating quantum dot conjugates. Nature Protocols 2006; 1: 1160-1164. PMID: 17406398 PDF

13. Cai W, Rao J, Gambhir SS, Chen X. How molecular imaging is speeding up antiangiogenic drug development. Molecular Cancer Therapeutics 2006; 5: 2624-2633. PMID: 17121909 PDF

12. Zhang Y, So M-K, Rao J. Protease-modulated cellular uptake of quantum dots. Nano Letters 2006; 6: 1988-1992. PMID: 16968013 PDF

| Back to top |


11. Xing B, Khanamiryan A, Rao J. Cell-permeable near-infrared fluorogenic substrates for imaging ▀-lactamase activity. Journal of American Chemical Society 2005; 127: 4158-4159. PMID: 15783183 PDF


10. Hasegawa S, Choi JW, Rao J. Single-cell detection of trans-splicing ribozyme in vivo activity. Journal of American Chemical Society 2004; 126: 7158-7159.PMID: 15186136 PDF

| Back to top |


9. Gao W, Xing B, Tsien RY, Rao J. Novel fluorogenic substrates for imaging ▀-lactamase expression. Journal of American Chemical Society 2003; 125: 11146-11147.PMID: 16220906 PDF

8. Hasegawa S, Jackson WC, Tsien RY, Rao J. Imaging Tetrahymena ribozyme splicing activity in single live mammalian cells. Proceedings of National Academy of Science USA 2003; 100: 14892-14896.PMID: 14645710 PDF

| Back to top |

Professor Rao's Publications from his graduate years working with George Whitesides

7. Rao J, Lahiri J, Weis RW, Whitesides GM. Design, syntheses, and characterization of a high-affinity trivalent system derived from vancomycin and L-Lys-D-Ala-D-Ala. Journal of American Chemical Society 2000; 122: 2698-2710.Web of Science PDF

6. Rao J, Yan L, Xu B, Whitesides GM. Using surface plasmon resonance to study the binding of vancomycin and its dimer to self-assembled monolayers presenting D-Ala-D-Ala. Journal of American Chemical Society 1999; 121: 2629-2630.Web of Science PDF

5. Rao J, Yan L, Lahiri J, Whitesides GM, Warren HS, Weis RM. Binding of a dimeric derivative of vancomycin with L-Lys-D-Ala-D-Lactate in solution and at a surface: insights into its enhanced activity against vancomycin-resistant bacteria. Chemistry & Biology 1999; 6:353-359.PMID: 10375541 PDF

4. Rao J, Lahiri J, Isaacs L, Weis RW, Whitesides GM. A trivalent system from vancomycinĽD-Ala-D-Ala with higher affinity than biotinĽavidin. Science 1998; 280: 708-711.PMID: 9563940 PDF

3. Colton IJ, Carbeck JD, Rao J, Whitesides GM. Affinity capillary electrophoresis: a physical-organic tool for studying interactions in biomolecular recognition. Electrophoresis 1998; 19: 367-382.PMID: 9551788 PDF

2. Rao J, Colton IJ, Whitesides GM. Using capillary electrophoresis to study the electrostatic interactions involved in the association of D-Ala-D-Ala with vancomycin. Journal of American Chemical Society 1997; 119: 9336-9340. Web of Science PDF

1. Rao J, Whitesides GM. Tight binding of a dimeric derivative of vancomycin with dimeric L-Lys-D-Ala-D-Ala. Journal of American Chemical Society 1997; 119: 10286-10290.Web of Science PDF

| Back to top |

Footer Links: