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Nanosensors

  1. So, M. K.;Xu, C.;Loening, A. M.; Gambhir, S. S.; Rao, J.Self-Illuminating Quantum Dot Conjugates for in vivo Imaging. Nat. Biotechnol.2006, 24, 339-343. pdf
  2. Xu, C.; Xing, B.; Rao. J. A self-Assembled Quantum Dot Probe for Detecting bet-Lactamase Activity. Biochem. Biophys. Res. Commun. 2006, 344, 931-935. pdf
  3.  Zhang, Y.; So, M. K.; Loening, A. M.; Yao, H.; Gambhir, S. S.; Rao, J. HaloTag Protein-Mediated Site-Specific Conjugation of Bioluminescent Proteins to Quantum Dots. Angew. Chem. Int. Ed. 2006, 45, 4936-4940.
  4. Zhang, Y. So, M.K.; Rao, J. Protease-Modulated Cellular Uptake of Quantum Dots. Nano Lett. 2006, 6, 1988-1992.
  5. So, M.K.; Loening, A. M.; Gambhir, S. S.; Rao, J. Creating Self-Illuminating Quantum Dot Conjugates. Nat. Protoc. 2006, 3, 1160-1164.
  6. Yao, H.; Zhang, Y.; Xiao, F.; Xia, Z.; Rao, J.; QD-BRET-Based Highly Sensitive Detection of Protease. Angew. Chem. Intl. Ed. 2007, 46, 4346-4349.

      Ribozyme/RNA

  1. Hasegawa, S.; Gowrishankar, G.; Rao, J. Detection of mRNA in Mammalian Cells with a Split Ribozyme Reporter. ChemBioChem. 2006, 7, 925-928.
  2. Hasegawa, S.; Rao, J. Modulating the Splicing Activity of Tetrahymena Ribozyme via RNA Self-assembly. FEBS Lett. 2006, 580, 1592-1596.
  3. Hasegawa, S.; Choi, J. W.; Rao, J. Single-Cell Detection of Trans-Splicing Ribozyme in vivo Activity. J. Am. Chem. Soc. 2004, 126, 7158-7159.
  4. Hasegawa, S.; Jackson, W. C.; Tsien, R. Y.; Rao, J. Imaging Tetrahymena Ribozyme Splicing Activity in Single Live Mammalian Cells. Proc. Natl. Acad. Sci. 2003, 100, 14892-14896. 

Reporter gene beta-lactamase

  1.  Xing, B.; Khanamiryan, A.; Rao, J. Cell-Permeable Near-Infrared Fluorogenic Substrates for Imaging beta-Lactamase Activity.  J. Am. Chem. Soc. 2005, 127, 4158-4159.
  2. Gao, W.; Xing, B.; Tsien, R. Y.; Rao, J.; Novel Fluorogenic Substrates for Imaging beta-Lactamase Gene Expression. J. Am. Chem. Soc. 2003, 125, 11146-11147.
  3. Yao, H.; So, M. K.; Rao, J. A Bioluminogenic Susbtrate for in vivo Imaging of Beta-Lactamase Activity. Angew. Chem. Intl. Ed. 2007, 46, In Press.

Invited Reviews

14.   Gowrishankar G,; Rao, J. Visualizing RNA Splicing in vivo. Mol. Biosyst. 2007, 3, 301-7.

15.   Dragulescu-Andrasi, A,; Rao, J. Chemical Labeling of Protein in Living Cells. Chembiochem. 2007, In press.

16.   Rao. J.; Dragulescu-Andrasi, A.; Yao, H. Fluorescence Imaging in vivo: Recent Advances. Curr. Opin. Biotechnol. 2007, 18, 17-25.

17.   Cai, W.; Rao, J.; Gambhir S.S.; Chen, X. Molecular imaging in Anti-Angiogenic Drug Development. Mol. Caner. Ther. 2006, 5, 2624-33.

Others

18.   Rao, J.; Colton, I. J.; Whitesides, G. M. Using Capillary Electrophoresis to Study the Electrostatic Interactions Involved in the Association of D-Ala-D-Ala with Vancomycin. J. Am. Chem. Soc. 1997, 119, 9336-9340.

19.   Rao, J.; Whitesides, G. M. Tight Binding of a Dimeric Derivative of Vancomycin with Dimeric L-Lys-D-Ala-D-Ala. J. Am. Chem. Soc. 1997, 119, 10286-10290.

20.   Rao, J.; Lahiri, J.; Isaacs, L.; Weis, R. W.; Whitesides, G. M. A Trivalent System from Vancomycin:D-Ala-D-Ala with Higher Affinity than Biotin:Avidin. Science 1998, 280, 708-711.

21.   Colton, I. J.; Carbeck, J. D.; Rao, J.; Whitesides, G. M. Affinity Capillary Electrophoresis: a Physical-Organic Tool for Studying Interactions in Biomolecular Recognition. Electrophoresis 1998, 19, 367-382.

22.   Rao, J.; Yan, L.; Xu, B.; Whitesides, G. M. Using Surface Plasmon Resonance to Study the Binding of Vancomycin and Its Ddimer to Self-Assembled Monolayers Presenting D-Ala-D-Ala. J. Am. Chem. Soc.  1999, 121, 2629-2630.

23.   Rao, J.; Yan, L.; Lahiri, J.; Whitesides, G. M.; Warren, H. S.; Weis, R. M. Binding of a Dimeric Derivative of Vancomycin with L-Lys-D-Ala-D-Lactate in Solution and at a Surface: Insights into Its Enhanced Activity Against Vancomycin-Resistant Bacteria. Chemistry & Biology 1999, 6, 353-359.

24.   Rao, J.; Lahiri, J.; Weis, R. W.; Whitesides, G. M. Design, Syntheses, and Characterization of a High-Affinity Trivalent System Derived from Vancomycin and L-Lys-D-Ala-D-Ala. J. Am. Chem. Soc. 2000, 122, 2698-2710. 

Last updated  06/07/2007