Jianghong Rao Lab In the Departments of Radiology and Chemistry

Lina Cui, Ph.D.

Lina Cui, Ph.D.

At Stanford, Lina’s research is focused on the development of “smart” imaging (fluorescent, photoacoustic, and MRI) molecules that can be activated and retained at diseased sites. Targeted enzymes currently include caspase-3 and poly (ADP-ribose) polymerase 1 (PARP-1).

Education and Professional Training:

Postdoctoral fellow 2009-2010
Topic: biomedical materials, vaccine/drug delivery
UC-Berkeley (Jean M.J. Fréchet group)

Ph.D. in chemistry 2003-2008
Topic: organic chemistry, glycobiology
Alberta Ingenuity Centre for Carbohydrate Science
University of Alberta, Edmonton, Canada (David R. Bundle group)

B.Sc. in Chemistry 1999-2003
Topic: organic chemistry
Nankai University, Tianjin, China (Li-Cheng Song group)

Awards and honors:

GSA Professional Development Grants, University of Alberta, Canada, 2008;
J. Gordin Kaplan Graduate Student Award, University of Alberta, Canada, 2008;
Yang Shi-Xian Scholarship, Nankai University, China, 2002;
First-Class Scholarship, Chinese Academy of Sciences, China, 2000;
First-Class National Scholarship, China, 2000-2003.

Recent Publications:

    1. Zhang, P., A. Wang, L. Cui, and C.-C. Ling*, First Per-6-O-tritylation of Cyclodextrins. Organic Letters, 2012. 14(6): p. 1612-1615.

    2. Cui, L., P.I. Kitov, G.C. Completo, J.C. Paulson, and D.R. Bundle*, Supramolecular Complexing of Membane Siglec CD22 Mediated by a Polyvalent Heterobifunctional Ligand that Templates on IgM. Bioconjugate Chemistry, 2011. 22(4): p. 546-550.

    3. Cui, L., J.A. Cohen, K.E. Broaders, T.T. Beaudette, and J.M.J. Frechet*, Mannosylated Dextran Nanoparticles: A pH-Sensitive System Engineered for Immunomodulation through Mannose Targeting. Bioconjugate Chemistry, 2011. 22(5): p. 949-957.

    4. Cohen, J.L., S. Schubert, P.R. Wich, L. Cui, J.A. Cohen, J.L. Mynar, and J.M.J. Frechet*, Acid-Degradable Cationic Dextran Particles for the Delivery of siRNA Therapeutics. Bioconjugate Chemistry, 2011. 22(6): p. 1056-1065.

    5. Wu, X., L. Cui, T. Lipinski, and D.R. Bundle*, Synthesis of Monomeric and Dimeric Repeating Units of the Zwitterionic Type 1 Capsular Polysaccharide from Streptococcus pneumoniae. Chemistry-a European Journal, 2010. 16(11): p. 3476- 3488.

    6. Humphries, R.M., M.S. Donnenberg, J. Strecker, E. Kitova, J.S. Klassen, L. Cui, T.P. Griener, G.L. Mulvey, and G.D. Armstrong*, From alpha to beta: identification of amino acids required for the N-acetyllactosamine-specific lectin-like activity of bundlin. Molecular Microbiology, 2009. 72(4): p. 859-868.

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