Jianghong Rao Lab In the Departments of Radiology and Chemistry

Yunfeng "Jerry" Cheng, Ph.D.



Yunfeng "Jerry" Cheng, Ph.D.

Jerry is highly interested in the development of new chemical tools for studying biological problems in human health and disease, and his current research focuses on the design of imaging probes for beta-lactamase, ROS, and 13C MR reporters.

Education:

Ph.D. in Organic Chemistry, 2006-2011
Department of Chemistry, Georgia State University, Atlanta, USA
Advisor: Professor Dr. Binghe Wang

Publications:

    1. Haibin Shi*, Cheng Y*, Kyung Hyun Lee, Robert F Luo, Niaz Banaei, and Jianghong, Rao. Engineering Stereochemistry of Cephalosporin for Specific Detection of Carbapenemase-Expressing Pathogenic Bacteria. Angew. Chem. Int. Ed. In press. DOI: 10.1002/anie.201402012R1. ( *Co-first author)
    2. Cheng, Y., Dai, C., Peng, H., Zheng, S., Jin, S., and Wang, B., Design, Synthesis, and Polymerase-Catalyzed Incorporation of Click-modified Boronic Acid-TTP Analogues. Chem. Asian J., 2011. 6, 2747-2752.
    3. Peng, H., Cheng, Y., Dai, C., King, A., Predmore, B., Lefer, D., and Wang, B., A Fluorescent Probe for Fast and Quantitative Detection of Hydrogen Sulfide in Blood. Angew. Chem. Int. Ed., 2011. 50, 9672-9675.
    4. Cheng, Y., Peng, H., and Wang, B., "Reversible Covalent Bond Toolbox" in "Supramolecular Chemistry: from Molecules to Nanomaterials" by WILEY-VCH; Ed.: Gale, P. and Steed, J., 2011.
    5. Cheng, Y., Ni, N., Peng, H., Jin, S., and Wang, B., "Carbohydrate Biomarkers" in "Carbohydrate Recognition: Biological Problems, Methods, and Applications" by WILEY-VCH; Ed.: Wang, B. and Boons, G-J, 2011. 133-156.
    6. Cheng, Y., Yang, X., and Wang, B., "Covalent Interactions in Chemosensor Design" in "Chemosensors: Principles, Strategies, and Applications" by WILEY-VCH; Ed.: Wang, B and Anslyn, E.A., 2011. 25-40.
    7. Yang, X., Cheng, Y., and Wang, B., "Synthetic Lectin Mimics Artificial Carbohydrate Receptors" in "Carbohydrate Recognition: Biological Problems, Methods, and Applications" by WILEY-VCH; Ed.: Wang, B. and Boons, G-J., 2011. 301-327.
    8. Cheng, Y., Ni, N., Yang, W., and Wang, B., A New Class of Fluorescent Boronic Acid that Have Extraordinarily High Binding Affinities for Diols in Aqueous Solution at Physilogical pH. Chem. Eur. J., 2010. 16, 13528-13538.
    9. Cheng, Y., Li, M., Wang, S., Peng, H., Reid, S., Ni, N., Fang, H., Xu, W., and Wang, B., Carbohydrate Biomarkers for Future Disease Detection and Treatment. Sci. China Chem., 2010. 53(1), 3-20.
    10. Yang, X., Cheng, Y., Jin, S., and Wang, B., "Boronic Acid-Based Chemosensors" in "Artificial Receptors for Chemical Sensors" by WILEY-VCH; Ed.: Mirsky, V.M. and Yatsimirsky, A.K., 2010. DOI: 10.1002/9783527632480.
    11. Jin, S., Cheng, Y., Reid, S., Li, M., and Wang, B., Carbohydrate Recognition by Boronolectins, Small Molecules, and Lectins. Med. Res. Rev., 2010, 30(2), 171-257.
    12. Dai, C., Cheng, Y., Cui, J., and Wang, B., "Click Reactions Involving the Boronic Acid Moiety: Applications and Potential Issues." in a special issues: "Click Chemistry". Molecules, 2010. 15(8), 5768-5781.
    13. Jin, S., Zhu, C., Cheng, Y., Li, M., and Wang, B., Synthesis and Carbohydrate Binding Studies of Fluorescent a-Amidoboronic Acids and the Corresponding Bisboronic Acids. Bioorg. Med. Chem., 2010, 18(4), 1449-1455.
    14. Peng, H.*, Cheng, Y.*, Ni, N., Li, M., Choudhary, G., Chou, H., Lu, C., Tai, P., and Wang, B., Synthesis and Evaluation of New Antagonists of Bacterial Quorum Sensing in Vibrio Harveyi. ChemMedChem, 2009. 4(9), 1457-1468. *Co-first author
    15. Jin, S., Choudhary, G., Cheng, Y., Dai, C., Li, M., and Wang, B., Fluoride Protects Boronic Acids in the Copper(I)-mediated Click Reaction. Chem. Commun., 2009. 35, 5251-5253.
    16. Cheng, Y., Hu, Y., and He, Q., Synthesis and Antitumor Activity of Arylsubstituted Imidazolin-2-one Derivatives. Acta. Pharm. Sin., 2005. 40, 711-716.
    17. Cheng, Y. and Hu, Y., One-pot Facile Synthesis of 1,3,4-trisubstituted Imidazolin-2-one. J. Chem. Res., 2004. 4, 292-293.
    18. Cheng, Y. and Hu, Y., Synthesis of Arylsubsituted Imidazolin-2-one Analogs. Chinese Chem. Lett., 2004. 15, 1281-1284.



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